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Optimized Threshold Inference for Partitioning of Clones From High-Throughput B Cell Repertoire Sequencing Data

During adaptive immune responses, activated B cells expand and undergo somatic hypermutation of their B cell receptor (BCR), forming a clone of diversified cells that can be related back to a common ancestor. Identification of B cell clones from high-throughput Adaptive Immune Receptor Repertoire se...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Nouri, Nima, Kleinstein, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070604/
https://ncbi.nlm.nih.gov/pubmed/30093903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01687
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