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Knockout of myoc Provides Evidence for the Role of Myocilin in Zebrafish Sex Determination Associated with Wnt Signalling Downregulation

SIMPLE SUMMARY: Myocilin is a protein with an incompletely understood function, mainly known because of its role in glaucoma. In this study we have analysed the normal role of this protein in vivo. To that end, we generated the first myocilin knockout zebrafish line reported to date. This zebrafish...

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Vydáno v:Biology (Basel)
Hlavní autoři: Atienzar-Aroca, Raquel, Aroca-Aguilar, José-Daniel, Alexandre-Moreno, Susana, Ferre-Fernández, Jesús-José, Bonet-Fernández, Juan-Manuel, Cabañero-Varela, María-José, Escribano, Julio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7912607/
https://ncbi.nlm.nih.gov/pubmed/33573230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10020098
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