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Interaction of Recombinant Myocilin with the Matricellular Protein SPARC: Functional Implications

PURPOSE. Myocilin is an extracellular glycoprotein with unknown function that is associated with glaucoma. Calpain II cleaves recombinant myocilin within the linker region of the protein, releasing the C-terminal olfactomedin domain from the N-terminal domain. The authors previously reported that my...

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Detalhes bibliográficos
Main Authors: Aroca-Aguilar, José-Daniel, Sánchez-Sánchez, Francisco, Ghosh, Sikha, Fernández-Navarro, Ana, Coca-Prados, Miguel, Escribano, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053273/
https://ncbi.nlm.nih.gov/pubmed/20926826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4866
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