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Functional Role of Proteolytic Processing of Recombinant Myocilin in Self-Aggregation
PURPOSE. Recombinant myocilin expressed in cells in culture is endoproteolytically cleaved in the endoplasmic reticulum by calpain II, releasing an N-terminal and a C-terminal fragment. This proteolytic processing has been speculated to regulate the molecular interactions of myocilin. The main purpo...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869055/ https://ncbi.nlm.nih.gov/pubmed/19696176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4118 |
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