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Null cyp1b1 Activity in Zebrafish Leads to Variable Craniofacial Defects Associated with Altered Expression of Extracellular Matrix and Lipid Metabolism Genes

SIMPLE SUMMARY: CYP1B1 is a cytochrome P450 monooxygenase involved in oxidative metabolism of different endogenous lipids and drugs. The loss of function (LoF) of this gene underlies many cases of recessive primary congenital glaucoma (PCG), an infrequent disease and a common cause of infantile loss...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Alexandre-Moreno, Susana, Bonet-Fernández, Juan-Manuel, Atienzar-Aroca, Raquel, Aroca-Aguilar, José-Daniel, Escribano, Julio
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234340/
https://ncbi.nlm.nih.gov/pubmed/34208498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126430
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