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Structural Insights into Substrate Recognition and Processing by the 20S Proteasome

Four decades of proteasome research have yielded extensive information on ubiquitin-dependent proteolysis. The archetype of proteasomes is a 20S barrel-shaped complex that does not rely on ubiquitin as a degradation signal but can degrade substrates with a considerable unstructured stretch. Since ro...

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Detalles Bibliográficos
Publicado en:Biomolecules
Autores principales: Sahu, Indrajit, Glickman, Michael H.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910952/
https://ncbi.nlm.nih.gov/pubmed/33498876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020148
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