AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo

Axonal damage is an early step in traumatic and neurodegenerative disorders of the central nervous system (CNS). Damaged axons are not able to regenerate sufficiently in the adult mammalian CNS, leading to permanent neurological deficits. Recently, we showed that inhibition of the autophagic protein...

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Publicado en:Cell Death Dis
Autores principales: Ribas, Vinicius Toledo, Vahsen, Björn Friedhelm, Tatenhorst, Lars, Estrada, Veronica, Dambeck, Vivian, Almeida, Raquel Alves, Bähr, Mathias, Michel, Uwe, Koch, Jan Christoph, Müller, Hans Werner, Lingor, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910615/
https://ncbi.nlm.nih.gov/pubmed/33637688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03503-3
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