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A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair
Bulky DNA lesions in transcribed strands block RNA polymerase II (RNAPII) elongation and induce a genome-wide transcriptional arrest. The transcription-coupled repair (TCR) pathway efficiently removes transcription-blocking DNA lesions, but how transcription is restored in the genome following DNA r...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7910549/ https://ncbi.nlm.nih.gov/pubmed/33637760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21520-w |
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