TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Transcription-blocking DNA lesions are removed by transcription-coupled nucleotide excision repair (TC-NER) to preserve cell viability. TC-NER is triggered by the stalling of RNA polymerase II at DNA lesions, leading to the recruitment of TC-NER-specific factors such as the CSA–DDB1–CUL4A–RBX1 culli...

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Publicado no:Nat Commun
Main Authors: Pines, Alex, Dijk, Madelon, Makowski, Matthew, Meulenbroek, Elisabeth M., Vrouwe, Mischa G., van der Weegen, Yana, Baltissen, Marijke, French, Pim J., van Royen, Martin E., Luijsterburg, Martijn S., Mullenders, Leon H., Vermeulen, Michiel, Vermeulen, Wim, Pannu, Navraj S., van Attikum, Haico
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847541/
https://ncbi.nlm.nih.gov/pubmed/29531219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03484-6
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