TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Transcription-blocking DNA lesions are removed by transcription-coupled nucleotide excision repair (TC-NER) to preserve cell viability. TC-NER is triggered by the stalling of RNA polymerase II at DNA lesions, leading to the recruitment of TC-NER-specific factors such as the CSA–DDB1–CUL4A–RBX1 culli...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Pines, Alex, Dijk, Madelon, Makowski, Matthew, Meulenbroek, Elisabeth M., Vrouwe, Mischa G., van der Weegen, Yana, Baltissen, Marijke, French, Pim J., van Royen, Martin E., Luijsterburg, Martijn S., Mullenders, Leon H., Vermeulen, Michiel, Vermeulen, Wim, Pannu, Navraj S., van Attikum, Haico
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847541/
https://ncbi.nlm.nih.gov/pubmed/29531219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03484-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi