A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

Bulky DNA lesions in transcribed strands block RNA polymerase II (RNAPII) elongation and induce a genome-wide transcriptional arrest. The transcription-coupled repair (TCR) pathway efficiently removes transcription-blocking DNA lesions, but how transcription is restored in the genome following DNA r...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: van den Heuvel, Diana, Spruijt, Cornelia G., González-Prieto, Román, Kragten, Angela, Paulsen, Michelle T., Zhou, Di, Wu, Haoyu, Apelt, Katja, van der Weegen, Yana, Yang, Kevin, Dijk, Madelon, Daxinger, Lucia, Marteijn, Jurgen A., Vertegaal, Alfred C. O., Ljungman, Mats, Vermeulen, Michiel, Luijsterburg, Martijn S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910549/
https://ncbi.nlm.nih.gov/pubmed/33637760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21520-w
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