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Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity

The innate immune response influences neural repair after spinal cord injury (SCI). Here, we combined myeloid-specific transcriptomics and single-cell RNA sequencing to uncover not only a common core but also temporally distinct gene programs in injury-activated microglia and macrophages (IAM). Intr...

詳細記述

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書誌詳細
出版年:Sci Adv
主要な著者: Wahane, Shalaka, Zhou, Xianxiao, Zhou, Xiang, Guo, Lei, Friedl, Marie-Sophie, Kluge, Michael, Ramakrishnan, Aarthi, Shen, Li, Friedel, Caroline C., Zhang, Bin, Friedel, Roland H., Zou, Hongyan
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909890/
https://ncbi.nlm.nih.gov/pubmed/33637528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd8811
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