HDAC3 inhibition ameliorates spinal cord injury by immunomodulation

Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizi...

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Pubblicato in:Sci Rep
Autori principali: Kuboyama, Tomoharu, Wahane, Shalaka, Huang, Yong, Zhou, Xiang, Wong, Jamie K., Koemeter-Cox, Andrew, Martini, Michael, Friedel, Roland H., Zou, Hongyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561061/
https://ncbi.nlm.nih.gov/pubmed/28819194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08535-4
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