HDAC3 inhibition ameliorates spinal cord injury by immunomodulation

Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizi...

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Foilsithe in:Sci Rep
Main Authors: Kuboyama, Tomoharu, Wahane, Shalaka, Huang, Yong, Zhou, Xiang, Wong, Jamie K., Koemeter-Cox, Andrew, Martini, Michael, Friedel, Roland H., Zou, Hongyan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561061/
https://ncbi.nlm.nih.gov/pubmed/28819194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08535-4
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