HDAC3 inhibition ameliorates spinal cord injury by immunomodulation

Following spinal cord injury (SCI), the innate immune response of microglia and infiltrating macrophages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses. Immunomodulation aimed at maximizing the beneficial effects while minimizi...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kuboyama, Tomoharu, Wahane, Shalaka, Huang, Yong, Zhou, Xiang, Wong, Jamie K., Koemeter-Cox, Andrew, Martini, Michael, Friedel, Roland H., Zou, Hongyan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561061/
https://ncbi.nlm.nih.gov/pubmed/28819194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08535-4
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