Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity

The innate immune response influences neural repair after spinal cord injury (SCI). Here, we combined myeloid-specific transcriptomics and single-cell RNA sequencing to uncover not only a common core but also temporally distinct gene programs in injury-activated microglia and macrophages (IAM). Intr...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Adv
Main Authors: Wahane, Shalaka, Zhou, Xianxiao, Zhou, Xiang, Guo, Lei, Friedl, Marie-Sophie, Kluge, Michael, Ramakrishnan, Aarthi, Shen, Li, Friedel, Caroline C., Zhang, Bin, Friedel, Roland H., Zou, Hongyan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Association for the Advancement of Science 2021
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909890/
https://ncbi.nlm.nih.gov/pubmed/33637528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd8811
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