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Lost structural and functional inter-relationships between Ig and TCR loci in mammals revealed in sharks

Immunoglobulins and T cell receptors (TCR) have obvious structural similarities as well as similar immunogenetic diversification and selection mechanisms. Nevertheless, the two receptor systems and the loci that encode them are distinct in humans and classical murine models, and the gene segments co...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunogenetics
Egile Nagusiak: Ott, Jeannine A., Ohta, Yuko, Flajnik, Martin F., Criscitiello, Michael F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909615/
https://ncbi.nlm.nih.gov/pubmed/33449123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-020-01183-5
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