Shark Class II Invariant Chain Reveals Ancient Conserved Relationships with Cathepsins and MHC Class II

The invariant chain (Ii) is the critical third chain required for the MHC class II heterodimer to be properly guided through the cell, loaded with peptide, and expressed on the surface of antigen presenting cells. Here, we report the isolation of the nurse shark Ii gene, and the comparative analysis...

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Hauptverfasser: Criscitiello, Michael F., Ohta, Yuko, Graham, Matthew D., Eubanks, Jeannine O., Chen, Patricia L., Flajnik, Martin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260380/
https://ncbi.nlm.nih.gov/pubmed/21996610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dci.2011.09.008
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