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Lost structural and functional inter-relationships between Ig and TCR loci in mammals revealed in sharks
Immunoglobulins and T cell receptors (TCR) have obvious structural similarities as well as similar immunogenetic diversification and selection mechanisms. Nevertheless, the two receptor systems and the loci that encode them are distinct in humans and classical murine models, and the gene segments co...
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| Veröffentlicht in: | Immunogenetics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7909615/ https://ncbi.nlm.nih.gov/pubmed/33449123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-020-01183-5 |
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