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An evolutionarily mobile antigen receptor variable region gene: Doubly rearranging NAR-TcR genes in sharks

Distinctive Ig and T cell receptor (TcR) chains define the two major lineages of vertebrate lymphocyte yet similarly recognize antigen with a single, membrane-distal variable (V) domain. Here we describe the first antigen receptor chain that employs two V domains, which are generated by separate VDJ...

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Detalhes bibliográficos
Main Authors: Criscitiello, Michael F., Saltis, Mark, Flajnik, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458790/
https://ncbi.nlm.nih.gov/pubmed/16549799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507074103
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