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Structural analysis of the nurse shark (new) antigen receptor (NAR): Molecular convergence of NAR and unusual mammalian immunoglobulins

We recently have identified an antigen receptor in sharks called NAR (new or nurse shark antigen receptor) that is secreted by splenocytes but does not associate with Ig light (L) chains. The NAR variable (V) region undergoes high levels of somatic mutation and is equally divergent from both Ig and...

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Autors principals: Roux, Kenneth H., Greenberg, Andrew S., Greene, Lesley, Strelets, Lioudmila, Avila, David, McKinney, E. Churchill, Flajnik, Martin F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21721/
https://ncbi.nlm.nih.gov/pubmed/9751746
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