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A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG

In most vertebrate embryos and neonates studied to date unique antigen receptors (antibodies and T cell receptors) are expressed that possess a limited immune repertoire. We have isolated a subclass of IgM, IgM(1gj), from the nurse shark Ginglymostoma cirratum that is preferentially expressed in neo...

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Detalhes bibliográficos
Main Authors: Rumfelt, Lynn L., Avila, David, Diaz, Marilyn, Bartl, Simona, McKinney, E. Churchill, Flajnik, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29333/
https://ncbi.nlm.nih.gov/pubmed/11172027
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