A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG

In most vertebrate embryos and neonates studied to date unique antigen receptors (antibodies and T cell receptors) are expressed that possess a limited immune repertoire. We have isolated a subclass of IgM, IgM(1gj), from the nurse shark Ginglymostoma cirratum that is preferentially expressed in neo...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Rumfelt, Lynn L., Avila, David, Diaz, Marilyn, Bartl, Simona, McKinney, E. Churchill, Flajnik, Martin F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2001
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29333/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11172027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1775
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