Structural analysis of the nurse shark (new) antigen receptor (NAR): Molecular convergence of NAR and unusual mammalian immunoglobulins

We recently have identified an antigen receptor in sharks called NAR (new or nurse shark antigen receptor) that is secreted by splenocytes but does not associate with Ig light (L) chains. The NAR variable (V) region undergoes high levels of somatic mutation and is equally divergent from both Ig and...

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Detalhes bibliográficos
Main Authors: Roux, Kenneth H., Greenberg, Andrew S., Greene, Lesley, Strelets, Lioudmila, Avila, David, McKinney, E. Churchill, Flajnik, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21721/
https://ncbi.nlm.nih.gov/pubmed/9751746
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