LRRK2 Modulates the Exocyst Complex Assembly by Interacting with Sec8

Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson’s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in the control of vesicle trafficking, likely by Rab p...

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Udgivet i:Cells
Main Authors: Fais, Milena, Sanna, Giovanna, Galioto, Manuela, Nguyen, Thi Thanh Duyen, Trần, Mai Uyên Thi, Sini, Paola, Carta, Franco, Turrini, Franco, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Crosio, Claudia, Iaccarino, Ciro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909581/
https://ncbi.nlm.nih.gov/pubmed/33498474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020203
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