LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization

The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physiological and pathological functions of LRRK2 are not...

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Detalhes bibliográficos
Main Authors: Migheli, Rossana, Del Giudice, Maria Grazia, Spissu, Ylenia, Sanna, Giovanna, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Galioto, Manuela, Rocchitta, Gaia, Biosa, Alice, Serra, Pier Andrea, Carri, Maria Teresa, Crosio, Claudia, Iaccarino, Ciro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805556/
https://ncbi.nlm.nih.gov/pubmed/24167564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077198
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