LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization

The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physiological and pathological functions of LRRK2 are not...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Migheli, Rossana, Del Giudice, Maria Grazia, Spissu, Ylenia, Sanna, Giovanna, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Galioto, Manuela, Rocchitta, Gaia, Biosa, Alice, Serra, Pier Andrea, Carri, Maria Teresa, Crosio, Claudia, Iaccarino, Ciro
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805556/
https://ncbi.nlm.nih.gov/pubmed/24167564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077198
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