LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization

The leucine-rich repeat kinase 2 (LRRK2) gene was found to play a role in the pathogenesis of both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large multi-domain protein that is expressed in different tissues. To date, the physiological and pathological functions of LRRK2 are not...

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Main Authors: Migheli, Rossana, Del Giudice, Maria Grazia, Spissu, Ylenia, Sanna, Giovanna, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Galioto, Manuela, Rocchitta, Gaia, Biosa, Alice, Serra, Pier Andrea, Carri, Maria Teresa, Crosio, Claudia, Iaccarino, Ciro
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805556/
https://ncbi.nlm.nih.gov/pubmed/24167564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077198
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