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Models of LRRK2 associated Parkinson’s disease

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common genetic causes of Parkinson’s disease (PD), and also one of the strongest genetic risk factors in sporadic PD. The LRRK2 protein contains a GTPase domain and a kinase domain, and several protein-protein interaction domain...

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Detalhes bibliográficos
Publicado no:Adv Neurobiol
Main Authors: Xiong, Yulan, Dawson, Ted M., Dawson, Valina L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535810/
https://ncbi.nlm.nih.gov/pubmed/28353284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-49969-7_9
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