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HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo
TDP-43 pathology is a disease hallmark that characterizes both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP). TDP-43 undergoes several posttranslational modifications that can change its biological activities and its aggregative propensity, which is a common ha...
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| Udgivet i: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7224392/ https://ncbi.nlm.nih.gov/pubmed/32409664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2580-3 |
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