HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo

TDP-43 pathology is a disease hallmark that characterizes both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP). TDP-43 undergoes several posttranslational modifications that can change its biological activities and its aggregative propensity, which is a common ha...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Sanna, Simona, Esposito, Sonia, Masala, Alessandra, Sini, Paola, Nieddu, Gabriele, Galioto, Manuela, Fais, Milena, Iaccarino, Ciro, Cestra, Gianluca, Crosio, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224392/
https://ncbi.nlm.nih.gov/pubmed/32409664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2580-3
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