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Tissue-specific adrenergic regulation of the L-type Ca(2+) channel Ca(V)1.2

Ca(2+) influx through the L-type Ca(2+) channel Cav1.2 triggers each heartbeat. The fight or flight response induces the release of the stress-response hormone norepinephrine to stimulate β adrenergic receptors, cAMP production, and protein kinase A activity to augment Ca(2+) influx through Cav1.2 a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Signal
Prif Awduron: Man, Kwun Nok Mimi, Bartels, Peter, Horne, Mary C., Hell, Johannes W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909005/
https://ncbi.nlm.nih.gov/pubmed/33443233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abc6438
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