Dynamic L-type Ca(V)1.2 channel trafficking facilitates Ca(V)1.2 clustering and cooperative gating

L-type Ca(V)1.2 channels are key regulators of gene expression, cell excitability and muscle contraction. Ca(V)1.2 channels organize in clusters throughout the plasma membrane. This channel organization has been suggested to contribute to the concerted activation of adjacent Ca(V)1.2 channels (e.g....

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Ghosh, Debapriya, Nieves-Cintrón, Madeline, Tajada, Sendoa, Brust-Mascher, Ingrid, Horne, Mary C., Hell, Johannes W., Dixon, Rose E., Santana, Luis F., Navedo, Manuel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407617/
https://ncbi.nlm.nih.gov/pubmed/29959960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2018.06.013
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