Down-regulation of Ca(V)1.2 channels during hypertension: how fewer Ca(V)1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle

Hypertension is a clinical syndrome characterized by increased arterial tone. Although the mechanisms are varied, the generally accepted view is that increased Ca(V)1.2 channel function is a common feature of this pathological condition. Here, we investigated the mechanisms underlying vascular dysfu...

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Detalhes bibliográficos
Main Authors: Tajada, Sendoa, Cidad, Pilar, Colinas, Olaia, Santana, L Fernando, López-López, José R, Pérez-García, M Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892470/
https://ncbi.nlm.nih.gov/pubmed/24167226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.265751
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