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β(2) Adrenergic Receptor Complexes with the L-Type Ca(2+) Channel Ca(V)1.2 and AMPA-Type Glutamate Receptors: Paradigms for Pharmacological Targeting of Protein Interactions

Formation of signaling complexes is crucial for the orchestration of fast, efficient, and specific signal transduction. Pharmacological disruption of defined signaling complexes has the potential for specific intervention in selected regulatory pathways without affecting organism-wide disruption of...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Man, Kwun Nok Mimi, Navedo, Manuel F., Horne, Mary C., Hell, Johannes W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029424/
https://ncbi.nlm.nih.gov/pubmed/31561738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010919-023404
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