Toluene Dioxygenase-Catalyzed cis-Dihydroxylation of Quinolines: A Molecular Docking Study and Chemoenzymatic Synthesis of Quinoline Arene Oxides

Molecular docking studies of quinoline and 2-chloroquinoline substrates at the active site of toluene dioxygenase (TDO), were conducted using Autodock Vina, to identify novel edge-to-face interactions and to rationalize the observed stereoselective cis-dihydroxylation of carbocyclic rings and format...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Boyd, Derek R., Sharma, Narain D., Loke, Pui L., Carroll, Jonathan G., Stevenson, Paul J., Hoering, Patrick, Allen, Christopher C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907597/
https://ncbi.nlm.nih.gov/pubmed/33644006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.619175
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados