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Regioselectivity and Enantioselectivity of Naphthalene Dioxygenase during Arene cis-Dihydroxylation: Control by Phenylalanine 352 in the α Subunit

The naphthalene dioxygenase (NDO) system catalyzes the first step in the degradation of naphthalene by Pseudomonas sp. strain NCIB 9816-4. The enzyme has a broad substrate range and catalyzes several types of reactions including cis-dihydroxylation, monooxygenation, and desaturation. Substitution of...

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Библиографические подробности
Главные авторы: Parales, Rebecca E., Resnick, Sol M., Yu, Chi-Li, Boyd, Derek R., Sharma, Narain D., Gibson, David T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC110994/
https://ncbi.nlm.nih.gov/pubmed/10986254
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