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Protein Aggregation Inhibitors as Disease-Modifying Therapies for Polyglutamine Diseases
The polyglutamine (polyQ) diseases are a group of inherited neurodegenerative diseases caused by the abnormal expansion of a CAG trinucleotide repeat that are translated into an expanded polyQ stretch in the disease-causative proteins. The expanded polyQ stretch itself plays a critical disease-causa...
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| Veröffentlicht in: | Front Neurosci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7907447/ https://ncbi.nlm.nih.gov/pubmed/33642983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.621996 |
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