Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity

BACKGROUND: Elucidation of lipid metabolism and accumulation mechanisms is of paramount importance to understanding obesity and unveiling therapeutic targets. In vitro cell models have been extensively used for these purposes, yet, they do not entirely reflect the in vivo setup. Conventional lipomas...

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Pubblicato in:Int J Obes (Lond)
Autori principali: Le Duc, Diana, Lin, Chen-Ching, Popkova, Yulia, Yang, Zuqin, Akhil, Velluva, Çakir, M. Volkan, Grunewald, Sonja, Simon, Jan-Christoph, Dietz, Andreas, Dannenberger, Dirk, Garten, Antje, Lemke, Johannes R., Schiller, Jürgen, Blüher, Matthias, Nono Nankam, Pamela Arielle, Rolle-Kampczyk, Ulrike, von Bergen, Martin, Kelso, Janet, Schöneberg, Torsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906903/
https://ncbi.nlm.nih.gov/pubmed/33235355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-020-00716-y
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