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ITSN1 regulates SAM68 solubility through SH3 domain interactions with SAM68 proline-rich motifs
SAM68 is an mRNA-binding protein involved in mRNA processing in the nucleus that forms membraneless compartments called SAM68 Nuclear Bodies (SNBs). We found that intersectin 1 (ITSN1), a multidomain scaffold protein harboring five soluble SH3 domains, interacts with SAM68 proline-rich motifs (PRMs)...
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| Pubblicato in: | Cell Mol Life Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer International Publishing
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904728/ https://ncbi.nlm.nih.gov/pubmed/32780150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03610-y |
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