Kinetic Insights into the Binding between the nSH3 Domain of CrkII and Proline-Rich Motifs in cAbl

The interaction between CrkII and cAbl is implicated in diverse cellular processes. This interaction starts with the binding of the N-terminal Src homology 3 (nSH3) domain of CrkII to the proline-rich motifs of cAbl (PRMs(cAbl)). Despite its critical importance, the detailed binding mechanism betwee...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Zeng, Danyun, Bhatt, Veer S., Shen, Qingliang, Cho, Jae-Hyun
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103021/
https://ncbi.nlm.nih.gov/pubmed/27806266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.09.029
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