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Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling

Dynamic modulation of cell adhesion is integral to a wide range of biological processes. The small guanosine triphosphatase (GTPase) Rap1 is an important regulator of cell–cell and cell–matrix adhesions. We show here that induced expression of activated Abl tyrosine kinase reduces Rap1-GTP levels th...

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Detalhes bibliográficos
Main Authors: Huang, XiaoDong, Wu, Diana, Jin, Hua, Stupack, Dwayne, Wang, Jean Y.J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582888/
https://ncbi.nlm.nih.gov/pubmed/19001122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801192
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