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Structure-guided design of a potent peptide inhibitor targeting the interaction between CRK and ABL kinase
CT-10 regulator of kinase (CRK) proteins play important roles in human cancer metastasis and invasion. Moreover, CRK proteins are the major phosphorylation substrates of ABL kinase and its oncogenic mutant BCR-ABL kinase. The interaction between CRK and BCR-ABL plays important roles in chronic myelo...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072116/ https://ncbi.nlm.nih.gov/pubmed/30108942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00619e |
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