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De Novo Design of Potent Antimicrobial Peptides

Lipopolysaccharide (LPS), shed by gram-negative bacteria during infection and antimicrobial therapy, may lead to lethal endotoxic shock syndrome. A rational design strategy based on the presumed mechanism of antibacterial effect was adopted to design cationic antimicrobial peptides capable of bindin...

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Detalhes bibliográficos
Main Authors: Frecer, V., Ho, B., Ding, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514781/
https://ncbi.nlm.nih.gov/pubmed/15328096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3349-3357.2004
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