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De Novo Design of Potent Antimicrobial Peptides
Lipopolysaccharide (LPS), shed by gram-negative bacteria during infection and antimicrobial therapy, may lead to lethal endotoxic shock syndrome. A rational design strategy based on the presumed mechanism of antibacterial effect was adopted to design cationic antimicrobial peptides capable of bindin...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514781/ https://ncbi.nlm.nih.gov/pubmed/15328096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3349-3357.2004 |
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