Structural Characterization of de Novo Designed L(5)K(5)W Model Peptide Isomers with Potent Antimicrobial and Varied Hemolytic Activities

In an effort to develop short antimicrobial peptides with simple amino acid compositions, we generated a series of undecapeptide isomers having the L(5)K(5)W formula. Amino acid sequences were designed to be perfectly amphipathic when folded into a helical conformation by converging leucines onto on...

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Publicado no:Molecules
Main Authors: Kim, Seo-Jin, Kim, Jae-Seok, Lee, Yoo-Sup, Sim, Dae-Won, Lee, Sung-Hee, Bahk, Young-Yil, Lee, Kwang-Ho, Kim, Eun-Hee, Park, Sung-Jean, Lee, Bong-Jin, Won, Hyung-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270530/
https://ncbi.nlm.nih.gov/pubmed/23344198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18010859
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