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Is It the Twilight of BACE1 Inhibitors?
β-secretase (BACE1) has been regarded as a prime target for the development of amyloid beta (Aβ) lowering drugs in the therapy of Alzheimer´s disease (AD). Although the enzyme was discovered in 1991 and helped to formulate the Aβ hypothesis as one of the very important features of AD etiopathogenesi...
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| Publicado no: | Curr Neuropharmacol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7903497/ https://ncbi.nlm.nih.gov/pubmed/32359337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X18666200503023323 |
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