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Developing BACE-1 inhibitors for FXS
Fragile X syndrome (FXS) is a debilitating genetic disorder with no cure and few therapeutic options. Excessive signaling through metabotropic glutamate receptor 5 in FXS leads to increased translation of numerous synaptic proteins and exaggerated long-term depression. Two of the overexpressed prote...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664772/ https://ncbi.nlm.nih.gov/pubmed/23754978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00077 |
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