Developing BACE-1 inhibitors for FXS

Fragile X syndrome (FXS) is a debilitating genetic disorder with no cure and few therapeutic options. Excessive signaling through metabotropic glutamate receptor 5 in FXS leads to increased translation of numerous synaptic proteins and exaggerated long-term depression. Two of the overexpressed prote...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Westmark, Cara J., Berry-Kravis, Elizabeth M., Ikonomidou, Chrysanthy, Yin, Jerry C. P., Puglielli, Luigi
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664772/
https://ncbi.nlm.nih.gov/pubmed/23754978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00077
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars