Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings

BACKGROUND: Intoxication by nerve agents could be prevented by using small acetylcholinesterase inhibitors (eg, pyridostigmine) for potentially exposed personnel. However, the serious side effects of currently used drugs led to research of novel potent molecules for prophylaxis of organophosphorus i...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Kuca, Kamil, Karasova, Jana Zdarova, Soukup, Ondrej, Kassa, Jiri, Novotna, Eva, Sepsova, Vendula, Horova, Anna, Pejchal, Jaroslav, Hrabinova, Martina, Vodakova, Eva, Jun, Daniel, Nepovimova, Eugenie, Valis, Martin, Musilek, Kamil
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2018
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849933/
https://ncbi.nlm.nih.gov/pubmed/29563775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S133038
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk