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Acetylcholinesterase Reactivators (HI-6, Obidoxime, Trimedoxime, K027, K075, K127, K203, K282): Structural Evaluation of Human Serum Albumin Binding and Absorption Kinetics

Acetylcholinesterase (AChE) reactivators (oximes) are compounds predominantly targeting the active site of the enzyme. Toxic effects of organophosphates nerve agents (OPNAs) are primarily related to their covalent binding to AChE and butyrylcholinesterase (BChE), critical detoxification enzymes in t...

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Detalles Bibliográficos
Main Authors: Zemek, Filip, Zdarova, Jana Karasova, Sepsova, Vendula, Kuca, Kamil
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759900/
https://ncbi.nlm.nih.gov/pubmed/23917882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816076
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