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Acetylcholinesterase Reactivators (HI-6, Obidoxime, Trimedoxime, K027, K075, K127, K203, K282): Structural Evaluation of Human Serum Albumin Binding and Absorption Kinetics

Acetylcholinesterase (AChE) reactivators (oximes) are compounds predominantly targeting the active site of the enzyme. Toxic effects of organophosphates nerve agents (OPNAs) are primarily related to their covalent binding to AChE and butyrylcholinesterase (BChE), critical detoxification enzymes in t...

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Bibliografiset tiedot
Päätekijät: Zemek, Filip, Zdarova, Jana Karasova, Sepsova, Vendula, Kuca, Kamil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Molecular Diversity Preservation International (MDPI) 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759900/
https://ncbi.nlm.nih.gov/pubmed/23917882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816076
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