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Acetylcholinesterase Reactivators (HI-6, Obidoxime, Trimedoxime, K027, K075, K127, K203, K282): Structural Evaluation of Human Serum Albumin Binding and Absorption Kinetics

Acetylcholinesterase (AChE) reactivators (oximes) are compounds predominantly targeting the active site of the enzyme. Toxic effects of organophosphates nerve agents (OPNAs) are primarily related to their covalent binding to AChE and butyrylcholinesterase (BChE), critical detoxification enzymes in t...

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Bibliografske podrobnosti
Main Authors: Zemek, Filip, Zdarova, Jana Karasova, Sepsova, Vendula, Kuca, Kamil
Format: Artigo
Jezik:Inglês
Izdano: Molecular Diversity Preservation International (MDPI) 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759900/
https://ncbi.nlm.nih.gov/pubmed/23917882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms140816076
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