A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

BACKGROUND: Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. METHODS: To determine if this reactivating efficacy would extend to huma...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Pharmacol Toxicol
Κύριοι συγγραφείς: Kuca, Kamil, Musilek, Kamil, Jun, Daniel, Zdarova-Karasova, Jana, Nepovimova, Eugenie, Soukup, Ondrej, Hrabinova, Martina, Mikler, John, Franca, Tanos C. C., Da Cunha, Elaine F. F., De Castro, Alexandre A., Valis, Martin, Ramalho, Teodorico C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2018
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822599/
https://ncbi.nlm.nih.gov/pubmed/29467029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0196-3
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