A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

BACKGROUND: Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. METHODS: To determine if this reactivating efficacy would extend to huma...

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書誌詳細
出版年:BMC Pharmacol Toxicol
主要な著者: Kuca, Kamil, Musilek, Kamil, Jun, Daniel, Zdarova-Karasova, Jana, Nepovimova, Eugenie, Soukup, Ondrej, Hrabinova, Martina, Mikler, John, Franca, Tanos C. C., Da Cunha, Elaine F. F., De Castro, Alexandre A., Valis, Martin, Ramalho, Teodorico C.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822599/
https://ncbi.nlm.nih.gov/pubmed/29467029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0196-3
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