A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

BACKGROUND: Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. METHODS: To determine if this reactivating efficacy would extend to huma...

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Foilsithe in:BMC Pharmacol Toxicol
Main Authors: Kuca, Kamil, Musilek, Kamil, Jun, Daniel, Zdarova-Karasova, Jana, Nepovimova, Eugenie, Soukup, Ondrej, Hrabinova, Martina, Mikler, John, Franca, Tanos C. C., Da Cunha, Elaine F. F., De Castro, Alexandre A., Valis, Martin, Ramalho, Teodorico C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822599/
https://ncbi.nlm.nih.gov/pubmed/29467029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0196-3
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