A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

BACKGROUND: Based on in vitro and in vivo rat experiments, the newly developed acetylcholinesterase (AChE) reactivator, K203, appears to be much more effective in the treatment of tabun poisonings than currently fielded oximes. METHODS: To determine if this reactivating efficacy would extend to huma...

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Detaylı Bibliyografya
Yayımlandı:BMC Pharmacol Toxicol
Asıl Yazarlar: Kuca, Kamil, Musilek, Kamil, Jun, Daniel, Zdarova-Karasova, Jana, Nepovimova, Eugenie, Soukup, Ondrej, Hrabinova, Martina, Mikler, John, Franca, Tanos C. C., Da Cunha, Elaine F. F., De Castro, Alexandre A., Valis, Martin, Ramalho, Teodorico C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822599/
https://ncbi.nlm.nih.gov/pubmed/29467029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0196-3
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