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Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon

The present work aimed to compare the small, neutral and monoaromatic oxime, isatin-3-oxime (isatin-O), to the commercial ones, pralidoxime (2-PAM) and obidoxime, in a search for a new potential reactivator for acetylcholinesterase (AChE) inhibited by the pesticide paraoxon (AChE/POX) as well as a n...

Полное описание

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Библиографические подробности
Опубликовано в: :Molecules
Главные авторы: de Paula, Reuel L., de Almeida, Joyce S. F. D., Cavalcante, Samir F. A., Gonçalves, Arlan S., Simas, Alessandro B. C., Franca, Tanos C. C., Valis, Martin, Kuca, Kamil, Nepovimova, Eugenie, Granjeiro, José M.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278417/
https://ncbi.nlm.nih.gov/pubmed/30424582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112954
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