Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon

The present work aimed to compare the small, neutral and monoaromatic oxime, isatin-3-oxime (isatin-O), to the commercial ones, pralidoxime (2-PAM) and obidoxime, in a search for a new potential reactivator for acetylcholinesterase (AChE) inhibited by the pesticide paraoxon (AChE/POX) as well as a n...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: de Paula, Reuel L., de Almeida, Joyce S. F. D., Cavalcante, Samir F. A., Gonçalves, Arlan S., Simas, Alessandro B. C., Franca, Tanos C. C., Valis, Martin, Kuca, Kamil, Nepovimova, Eugenie, Granjeiro, José M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278417/
https://ncbi.nlm.nih.gov/pubmed/30424582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112954
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