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Deconstructing Pancreatic Adenocarcinoma by Targeting the Conductor, MYC

In this issue of Cancer Discovery , Sodir and colleagues employ a pancreatic ductal adenocarcinoma mouse model with mutant KRAS and inducible MYC to demonstrate that MYC acts as a reversible driver of malignant tumor progression. Abrogation of MYC triggers rapid regression and disassembly of the ens...

詳細記述

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書誌詳細
出版年:Cancer Discov
主要な著者: English, Isabel A., Sears, Rosalie C.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902157/
https://ncbi.nlm.nih.gov/pubmed/32238397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0046
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